Bisphosphonates

Dental implant treatment considerations for patients taking Bisphosphonates   Bisphosphonates (both oral and intravenous) are used to manage osteoporosis as well as certain types of cancers. These compounds are potent inhibitors of osteoclastic-mediated bone resorption. Therefore, physiologic bone resorption and remodeling are severely compromised in patients receiving bisphosphonate therapy. Additionally, bisphosphonates have antiangiogenic properties and may be directly tumoricidal, making them an important agent in cancer therapy. All bisphosphonate compounds accumulate over extended periods of